FCGR3Bcopy number loss rather than gain is a risk factor for systemic lupus erythematous and lupus nephritis: a meta-analysis
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چکیده
منابع مشابه
Systemic Lupus Erythematous and Malignancy Risk: A Meta-Analysis
BACKGROUND Pilot studies have estimated cancer incidence in patients with systemic lupus erythematous (SLE). However, the results have been inconclusive. To ascertain the correlation between SLE and malignancy more comprehensively and precisely, we conducted a meta-analysis. METHODS PubMed, the Cochrane Library and Embase databases through June 2014, were searched to identify observational st...
متن کاملThe chemokine network in systemic lupus erythematous nephritis.
In response to renal immune complex accumulation in systemic lupus erythematosus (SLE), monocytes, T lymphocytes, and neutrophils infiltrate the kidney and mediate tissue injury and renal dysfunction. Chemotactic factors induced by immune complexes are responsible for recruiting these inflammatory cells to the kidney. Considerable attention has focused on the role of the chemokine network in re...
متن کاملDeveloping consensus treatment plans for proliferative lupus nephritis in childhood-onset systemic lupus erythematous
Purpose The SLE Subcommittee of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) is developing standardized treatment plans for proliferative lupus nephritis (LN) in childhood-onset SLE (cSLE) which will serve as the basis for future comparative effectiveness studies. The Initial Delphi survey revealed wide variability in the treatment of LN in cSLE. This abstract decribes the...
متن کاملIs systemic lupus erithematosus a new risk factor for atherosclerosis?
OBJECTIVE To evaluate the prevalence of cardiovascular events (CVE) secondary to atherosclerosis in lupus patients and correlate them to the traditional risk factors, disease duration and drug therapy used. METHODS A retrospective study was carried out based on data obtained from patients charts. Patients included were those who had a lupus diagnosis confirmed at least two years before inclus...
متن کاملImmunosenescence, Aging, and Systemic Lupus Erythematous
Senescence is a normal biological process that occurs in all organisms and involves a decline in cell functions. This process is caused by molecular regulatory machinery alterations, and it is closely related to telomere erosion in chromosomes. In the context of the immune system, this phenomenon is known as immunosenescence and refers to the immune function deregulation. Therefore, functions o...
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ژورنال
عنوان ژورنال: International Journal of Rheumatic Diseases
سال: 2014
ISSN: 1756-1841
DOI: 10.1111/1756-185x.12342